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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAPN5
All Species:
12.73
Human Site:
T578
Identified Species:
25.45
UniProt:
O15484
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15484
NP_004046.2
640
73169
T578
K
K
L
S
Q
P
I
T
V
Q
V
W
N
H
R
Chimpanzee
Pan troglodytes
XP_001146965
641
74541
P577
Y
R
R
T
T
D
I
P
I
I
V
Q
V
W
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542293
640
73142
T578
K
K
P
G
Q
P
I
T
V
Q
V
W
K
H
R
Cat
Felis silvestris
Mouse
Mus musculus
O08688
640
72936
T578
K
K
L
A
Q
P
I
T
V
Q
V
W
N
H
R
Rat
Rattus norvegicus
Q8R4C0
640
73046
T578
K
K
L
S
Q
P
I
T
V
Q
V
W
N
N
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518356
408
46381
Q362
L
S
D
E
F
L
G
Q
V
T
L
T
G
D
P
Chicken
Gallus gallus
Q92177
810
93542
I657
I
A
G
D
D
M
E
I
C
R
E
E
L
R
N
Frog
Xenopus laevis
NP_001080808
642
73235
P578
Y
R
K
K
P
G
Q
P
I
V
V
Q
V
W
N
Zebra Danio
Brachydanio rerio
XP_001345114
642
73723
G578
Y
R
K
K
P
K
E
G
I
H
I
E
I
Y
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q11002
828
93944
A635
N
M
A
F
E
T
Q
A
A
G
P
G
D
D
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22036
648
73596
K589
S
K
N
R
Q
Q
Y
K
I
E
V
W
E
D
R
Sea Urchin
Strong. purpuratus
XP_792213
642
72430
G576
I
F
Y
R
R
K
P
G
T
P
I
I
V
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.4
N.A.
92
N.A.
92.1
90.6
N.A.
51.4
30.8
73.9
71.6
N.A.
30.7
N.A.
40.1
47.6
Protein Similarity:
100
65.5
N.A.
95.6
N.A.
96
94.8
N.A.
57.3
46.9
86.2
83.8
N.A.
45.2
N.A.
57.2
64.9
P-Site Identity:
100
13.3
N.A.
80
N.A.
93.3
93.3
N.A.
6.6
0
6.6
0
N.A.
0
N.A.
33.3
0
P-Site Similarity:
100
33.3
N.A.
80
N.A.
100
100
N.A.
13.3
6.6
20
26.6
N.A.
13.3
N.A.
46.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
9
0
0
0
9
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
0
9
9
9
9
0
0
0
0
0
0
9
25
0
% D
% Glu:
0
0
0
9
9
0
17
0
0
9
9
17
9
9
0
% E
% Phe:
0
9
0
9
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
9
0
9
9
17
0
9
0
9
9
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
25
0
% H
% Ile:
17
0
0
0
0
0
42
9
34
9
17
9
9
0
0
% I
% Lys:
34
42
17
17
0
17
0
9
0
0
0
0
9
0
0
% K
% Leu:
9
0
25
0
0
9
0
0
0
0
9
0
9
0
0
% L
% Met:
0
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
9
0
0
0
0
0
0
0
0
0
25
9
34
% N
% Pro:
0
0
9
0
17
34
9
17
0
9
9
0
0
0
9
% P
% Gln:
0
0
0
0
42
9
17
9
0
34
0
17
0
0
0
% Q
% Arg:
0
25
9
17
9
0
0
0
0
9
0
0
0
9
42
% R
% Ser:
9
9
0
17
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
9
9
9
0
34
9
9
0
9
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
42
9
59
0
25
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
42
0
17
0
% W
% Tyr:
25
0
9
0
0
0
9
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _